What Is DHM?
Dihydromyricetin (DHM), also called ampelopsin, is a flavonoid compound extracted from the Japanese Raisin Tree (Hovenia dulcis). The plant has been used in East Asian medicine for over a thousand years specifically to reduce the effects of alcohol consumption.
How Does DHM Work?
DHM is included in hangover supplements for two primary reasons. First, it supports alcohol metabolism — specifically the liver's conversion of acetaldehyde (a toxic intermediate) into harmless acetate. Second, it has been shown to interact with GABA-A receptors, the same receptors that alcohol binds to, which is relevant to hangxiety (next-morning anxiety) and helping the nervous system recover from alcohol's sedative effect.
What Dose Is Effective?
Most DHM supplements on the market contain between 100mg and 400mg per dose. 300mg is a commonly used dose that sits in a well-studied range. Revive Capsules contains 300mg of DHM per dose — not the maximum available but a solid, evidence-consistent amount.
When to Take DHM
Timing is critical. DHM taken before bed after drinking is active during the metabolic processing window — when your liver is doing the work. DHM taken in the morning offers little benefit because the processing is mostly done.
Some users take a double dose: one before drinking begins and one before bed. This approach is used by people who drink heavily or who've had poor results with single dosing. For moderate drinking, a single pre-bed dose is sufficient for most people.
What to Look for When Buying
Avoid supplements with proprietary blends that don't disclose individual ingredient amounts. Look for at least 200mg DHM, with 300mg being the target. Check that the formula also includes milk thistle and B vitamins — DHM alone addresses alcohol metabolism but not B vitamin depletion.
Not all DHM is the same purity. When evaluating supplements, look for brands that are transparent about sourcing and standardisation. Revive uses a consistent, standardised DHM extract.